Department of Computer Science
What is The Plant MAPK Network Resource?
This is a general repository of MAPK, MKK sequences and orthologues in the plant kingdom. Orthologues were inferred using the InParanoid and Plaza orthologue identifier programs. This site also contains pointers to published evidence for constructing MAPK networks in Arabidopsis Yeast and Human, including high throughput and targeted experiments. The base dataset included here appeared in the paper by Dóczi, Ökrész, Romero, Paccanaro and Bögre (see reference). This dataset is continuously being refined and it is maintained by the staff at PaccanaroLab. If you wish to add a new entry or point out a missing entry, contact Dr. Alberto Paccanaro at: alberto - at - cs.rhul.ac.uk or Prof. László Bögre at: l.bogre - at - rhul.ac.ukThe dataset
MAPK and MEK sequences in plants
Orthologs of Arabidopsis MAPKs and MKKs as suggested by ortholog identifier programs:
- Orthologs of Arabidopsis MAPKs as determined by the InParanoid ortholog identifier program
- Orthologs of Arabidopsis MAPKs as determined by the PLAZA plan comparative genomics platform
- Orthologs of Arabidopsis MKKs as determined by the PLAZA plant comparative genomics platform
- Orthologs of Arabidopsis MKKs as determined by the InParanoid ortholog identifier platform
References for MKK-MPK interactions
MAPK and MEK sequences in plants
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MAPK and MKK sequences in green plants and in Naegleria |
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MAPK: TDY |
MAPK: TEY |
ERK8-like |
MHK |
MKK |
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Naegleria gruberi |
0 |
1 |
1 |
2 |
2 |
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XP_002672114 |
XP_002675531 |
XP_002675576 |
XP_002675852 |
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Chlamydomonas reinhardtii |
2 |
3 |
1 |
2 |
2 |
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XP_001703601 |
XP_001690852 |
XP_001699095 |
XP_001697865 |
XP_001696437 |
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Volvox carteri |
2 |
2 |
1 |
2 |
2 |
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XP_002954138 |
XP_002955338 |
XP_002951120 |
XP_002948753 |
XP_002947566 |
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Micromonas sp. |
1 |
2 |
1 |
2 |
2 |
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XP_002503335 |
XP_002503699 |
XP_002507666 |
XP_002502211 |
XP_002504085 |
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Ostreococcus tauri |
1 |
2 |
0 |
0 |
1 |
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XP_003080614 |
XP_003081390 |
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XP_003078923 |
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Ostreococcus lucimarinus |
1 |
2 |
0 |
0 |
1 |
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XP_001419059 |
XP_001419851 |
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XP_001417318 |
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Physcomitrella patens |
2 |
6 |
1 |
5 |
7 |
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XP_001765894
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XP_001771474 |
XP_001766838 |
XP_001758774 |
XP_001755215 |
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Selaginella moellendorffii |
4 |
4 |
2 |
4 |
5 |
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XP_002984293 |
XP_002967096 |
XP_002977037 |
XP_002987235 |
XP_002968717 |
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Populus trichocarpa |
9 |
13 |
0 |
5 |
11 |
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XP_002322093 |
XP_002298015 |
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XP_002301806 |
XP_002315388 |
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Oryza sativa |
9 |
6 |
0 |
3 |
7 |
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NP_001043794 |
NP_001061028 |
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NP_001056617 |
NP_001057028 |
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Arabidopsis thaliana |
8 |
12 |
0 |
3 |
10 |
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MAPK8
AT1G18150 |
MAPK1
AT1G10210 |
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MAPK21
AT4G13020 |
MKK1
AT4G26070 |
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Top Orthologs of Arabidopsis MAPKs and MKKs as suggested by ortholog identifier programs
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Arabidopsis thaliana |
Selaginella moellendorffii |
Physcomitrella patens |
Chlamydomonas reinhardtii |
Volvox carteri |
Ostreococcus lucimarinus |
Ostreococcus tauri |
Micromonas sp. RCC299 |
Naegleria gruberi |
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MAPK |
TDY |
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Group D |
MPK8 AT1G18150 |
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XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
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MPK9 AT3G18040 |
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XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
XP_002672114_nag |
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MPK15 AT1G73670 |
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XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
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MPK16 AT5G19010 |
XP_002961155_sel |
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XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
XP_002672114_nag |
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XP_002966854_sel |
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MPK17 AT2G01450 |
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XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
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MPK18 AT1G53510 |
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XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
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MPK19 AT3G14720 |
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XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
XP_002672114_nag |
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MPK20 AT2G42880 |
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XP_001765894_phy |
XP_001694300_chl |
XP_002954367_vol |
XP_001419059_olu |
XP_003080614_ota |
XP_002503335_mic |
XP_002672114_nag |
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XP_001766825_phy |
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TEY |
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Group C |
MPK1 AT1G10210 |
XP_002967096_sel |
XP_001776547_phy |
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XP_002672114_nag |
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XP_002960915_sel |
XP_001771474_phy |
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XP_002976409_sel |
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MPK2 AT1G59580 |
XP_002967096_sel |
XP_001776547_phy |
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XP_002672114_nag |
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XP_002960915_sel |
XP_001771474_phy |
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XP_002976409_sel |
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MPK7 AT2G18170 |
XP_002967096_sel |
XP_001776547_phy |
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XP_002672114_nag |
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XP_002960915_sel |
XP_001771474_phy |
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XP_002976409_sel |
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MPK14 AT4G36450 |
XP_002967096_sel |
XP_001776547_phy |
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XP_002672114_nag |
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XP_002960915_sel |
XP_001771474_phy |
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XP_002976409_sel |
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Group B |
MPK5 AT4G11330 |
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XP_002672114_nag |
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MPK11 AT1G01560 |
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MPK13 AT1G07880 |
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XP_001700291_chl |
XP_002955338_vol |
XP_001419851_olu |
XP_003081390_ota |
XP_002503699_mic |
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MPK12 AT2G46070 |
XP_002976336_sel |
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XP_001700291_chl |
XP_002955338_vol |
XP_001419851_olu |
XP_003081390_ota |
XP_002501054_mic |
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MPK4 AT4G01370 |
XP_002976336_sel |
XP_001763232_phy |
XP_001700291_chl |
XP_002955338_vol |
XP_001419851_olu |
XP_003081390_ota |
XP_002501054_mic |
XP_002672114_nag |
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Group A |
MPK6 AT2G43790 |
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XP_001700291_chl |
XP_002955338_vol |
XP_001419851_olu |
XP_003081390_ota |
XP_002503699_mic |
XP_002672114_nag |
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MPK3 AT3G45640 |
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XP_001700291_chl |
XP_002955338_vol |
XP_001419851_olu |
XP_003081390_ota |
XP_002501054_mic |
XP_002672114_nag |
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MPK10 AT3G59790 |
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XP_001700291_chl |
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XP_001419851_olu |
XP_003081390_ota |
XP_002503699_mic |
XP_002672114_nag |
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MHK |
MPK21AT4G13020 |
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MPK22 At4G19110 |
XP_002987235_sel |
XP_001757612_phy |
XP_001697865_chl |
XP_002949787_vol |
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XP_002505908_mic |
XP_002675576_nag |
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XP_001785524_phy |
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XP_001774238_phy |
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MPK23 At5G45430 |
XP_002987235_sel |
XP_001757612_phy |
XP_001697865_chl |
XP_002949787_vol |
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XP_002505908_mic |
XP_002675576_nag |
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XP_001785524_phy |
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XP_001774238_phy |
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Top Orthologs of Arabidopsis MAPKs as determined by the PLAZA plant comparative genomics platform |
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Arabidopsis thaliana |
Selaginella moellendorffii |
Physcomitrella patens |
Chlamydomonas reinhardtii |
Volvox carteri |
Ostreococcus lucimarinus |
Ostreococcus tauri |
Micromonas sp. RCC299 |
Naegleria gruberi |
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Group D |
8,9,15,16,17,18,19,20 |
XP_002966854 |
XP_001765894 |
XP_001694300 |
XP_002954367 |
XP_001419059 |
XP_003080614 |
XP_002503335 |
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XP_002984293 |
XP_001766825 |
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Group C |
1,2,7,14 |
XP_002960915 |
XP_001771474 |
XP_001690850 |
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Group B |
4,11,12 |
XP_002976336 |
XP_001763232 |
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XP_002503699 |
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Group A |
6 |
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XP_001700291 |
XP_002955338 |
XP_001419851 |
XP_003081390 |
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3,5,10,13 no ortholog |
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MHK |
21.22 |
XP_002976402 |
XP_001757612 |
XP_001697865 |
XP_002949787 |
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XP_002505908 |
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XP_001774238 |
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XP_001785524 |
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23 no ortholog |
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Orthologs of Arabidopsis MKKs as determined by the PLAZA plant comparative genomics platform |
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Arabidopsis thaliana |
Selaginella moellendorffii |
Physcomitrella patens |
Chlamydomonas reinhardtii |
Volvox carteri |
Ostreococcus lucimarinus |
Ostreococcus tauri |
Micromonas sp. RCC299 |
Naegleria gruberi |
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Group A |
MKK6 AT5G56580 |
XP_002968717 |
XP_001758355 |
XP_001693665 |
XP_002947566 |
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XP_002504085 |
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XP_001761737 |
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XP_001768791 |
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Group B |
MKK3 AT5G40440 |
XP_002960466 |
XP_001767359 |
XP_001696437 |
XP_002958286 |
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XP_002506404 |
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XP_001772493 |
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Group D |
MKK9 AT1G73500 |
XP_002991584 |
XP_001755215 |
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XP_001769374 |
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1,2,4,5,7,8,10 no ortholog |
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Orthologs of Arabidopsis MKKs as determined by the InParanoid ortholog identifier program |
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Arabidopsis thaliana |
Selaginella moellendorffii |
Physcomitrella patens |
Chlamydomonas reinhardtii |
Volvox carteri |
Ostreococcus lucimarinus |
Ostreococcus tauri |
Micromonas sp. RCC299 |
Naegleria gruberi |
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Group A |
MKK1 |
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XP_002947566_vol |
XP_001417318_olu |
XP_003078923_ota |
XP_002504085_mic |
XP_002675852_nag |
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MKK2 |
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XP_002947566_vol |
XP_001417318_olu |
XP_003078923_ota |
XP_002504085_mic |
XP_002675852_nag |
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MKK6 |
XP_002988344_sel |
XP_001758355_phy |
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XP_002947566_vol |
XP_001417318_olu |
XP_003078923_ota |
XP_002504085_mic |
XP_002675852_nag |
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XP_001768791_phy |
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Group B |
MKK3 |
XP_002960466_sel |
XP_001767359_phy |
XP_001696437_chl |
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XP_001417318_olu |
XP_003078923_ota |
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XP_002675852_nag |
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XP_001772493_phy |
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Group C |
MKK4 |
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MKK5 |
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Group D |
MKK7 |
XP_002991584_sel |
XP_001769374_phy |
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XP_002968717_sel |
XP_001755215_phy |
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MKK8 |
XP_002991584_sel |
XP_001769374_phy |
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XP_002968717_sel |
XP_001755215_phy |
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MKK9 |
XP_002991584_sel |
XP_001769374_phy |
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XP_002968717_sel |
XP_001755215_phy |
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MKK10 |
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Top
Yeast |
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Interaction |
References (low throughput) |
References (high throughput) |
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MKK1 → SLT2 |
PUBMED:9493378, PUBMED:8596433, PUBMED:17711850, PUBMED:8596433, PUBMED:22006927 |
PUBMED:20489023, PUBMED:21118957 |
|
MKK2 → SLT2 |
PUBMED:11805837, PUBMED:8596433, PUBMED:17711850, PUBMED:8757399 |
PUBMED:20489023, PUBMED:11805837 |
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PBS2 → HOG1 |
PUBMED:9180081, PUBMED:18212044, PUBMED:21698101 |
PUBMED:21118957 |
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STE7 → FUS3 |
PUBMED:19303851, PUBMED:8668180, PUBMED:15456892, PUBMED:8384702 |
PUBMED:20489023, PUBMED:21118957 |
|
STE7 → HOG1 |
PUBMED:20489023 |
PUBMED:20489023 |
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STE7 → KSS1 |
PUBMED: 19303851, PUBMED:11805837, PUBMED:8668180 |
PUBMED:20489023 |
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Top
Human |
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Interactions |
References (low throughput) |
References (high throughput) |
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MEK1 → MAPK1 |
PUBMED:10757792 PUBMED:11134045 PUBMED:11226259 PUBMED:11266467 PUBMED:11279118 PUBMED:11352917 PUBMED:11741894 PUBMED:11823456 PUBMED:12697810 PUBMED:16887817 PUBMED:17255949 PUBMED:17367534 PUBMED:8670897 |
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MEK1 → MAPK3 |
PUBMED:10748187 PUBMED:11134045 PUBMED:17367534 PUBMED:19197339 PUBMED:8226933 PUBMED:8626767 PUBMED:9006895 PUBMED:9733512 |
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MEK2 → MAPK1 |
PUBMED:11823456 |
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MEK2 → MAPK3 |
PUBMED:8626767 PUBMED:8226933 PUBMED:9006895 |
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MEK3 → MAPK14 |
PUBMED:17255949 PUBMED:11279118 |
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MEK3 → MAPK3 |
PUBMED:8226933 |
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MEK4 → MAPK8 |
PUBMED:11823456 PUBMED:10713157 PUBMED:11279118 |
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MEK4 → MAPK9 |
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PUBMED:21900206 |
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MEK5 → MAPK7 |
PUBMED:7759517 |
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MEK6 → MAPK14 |
PUBMED:17255949 PUBMED:12697810 PUBMED:8622669 PUBMED:11279118 |
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MEK7 → MAPK8 |
PUBMED:10713157 PUBMED:9207092 |
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MEK7 → MAPK14 |
PUBMED:9207092 |
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Top
Arabidopsis |
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Interactions |
References (low throughput) |
References (high throughput) |
|
MKK1 → MPK4 |
PUBMED:18982020; PUBMED:9878570; PUBMED:9804171; PUBMED:19513235; PUBMED:15225555 |
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MKK1 → MPK11 |
PUBMED:19513235 |
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MKK1 → MPK12 |
PUBMED:19000167 |
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MKK1 → MPK3 |
PUBMED:17059410 |
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MKK1 → MPK6 |
PUBMED:17059410 |
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MKK2 → MPK4 |
PUBMED:18982020; PUBMED:9878570; PUBMED:19513235; PUBMED:15225555 |
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MKK2 → MPK5 |
PUBMED:15225555 |
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MKK2 → MPK6 |
PUBMED:19513235; PUBMED:15225555 |
PUBMED:21798944 |
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MKK2 → MPK10 |
PUBMED:19513235 |
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MKK2 → MPK11 |
PUBMED:19513235 |
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MKK2 → MPK13 |
PUBMED:19513235 |
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MKK3 → MPK1 |
PUBMED:19513235 |
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MKK3 → MPK2 |
PUBMED:19513235 |
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MKK3 → MPK7 |
PUBMED:19513235 |
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MKK3 → MPK14 |
PUBMED:19513235 |
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MKK3 → MPK6 |
PUBMED:21419340 |
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MKK3 → MPK8 |
PUBMED:17369371 |
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MKK4 → MPK3 |
PUBMED:19513235 |
PUBMED:21798944 |
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MKK4 → MPK6 |
PUBMED:19513235 |
PUBMED:21798944 |
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MKK5 → MPK3 |
Doczi unpublished |
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MKK5 → MPK6 |
PUBMED:19513235 |
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MKK6 → MPK4 |
PUBMED:21575092; PUBMED:20802223; PUBMED:19513235 |
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MKK6 → MPK6 |
PUBMED:21575092; PUBMED:19513235 |
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MKK6 → MPK11 |
PUBMED:21575092; PUBMED:19513235 |
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MKK6 → MPK12 |
PUBMED:20802223; PUBMED:19000167 |
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MKK6 → MPK13 |
PUBMED:21575092; PUBMED:20802223; PUBMED:19513235 |
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MKK7 → MPK2 |
PUBMED:19513235 |
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MKK7 → MPK12 |
PUBMED:19000167 |
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MKK7 → MPK15 |
PUBMED:19513235 |
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MKK9 → MPK6 |
PUBMED:19513235 |
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MKK9 → MPK10 |
PUBMED:19513235 |
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MKK9 → MPK12 |
PUBMED:19000167 |
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MKK9 → MPK17 |
PUBMED:19513235 |
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MKK9 → MPK20 |
PUBMED:19513235 |
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MKK10 → MPK17 |
PUBMED:19513235 |
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